VCB and PowerPath compatibility Matrix
Recently a customer asked if VMware Consolidated Backup worked with PowerPath. After Googling around a bit, I came across this VMware KB article.
It has a great matrix of VCB versions and PowerPath versions (other vendor software is represented as well):
As long as you are using the later versions of PowerPath (32 bit only though) and the later versions of VCB, you will be leveraging the technology and features to the fullest. I normally see VCB in use on fiber storage networks where clients can see real benefit by moving the storage traffic off the network and onto the storage fabric.